Author

Daan van der Es

Leiden UniversityORCID 0000-0003-3662-8177Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Alisa GlukhovaiD· 1 shared Anh T. N. NguyeniD· 1 shared Arthur ChristopoulosiD· 1 shared David M. ThaliD· 1 shared Felix M. BennettsiD· 1 shared Hariprasad VenugopaliD· 1 shared Jesse I. MobbsiD· 1 shared Laura H. HeitmaniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPharmacology & Toxicology

Alisa GlukhovaORCID

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1 paper

Recent·Most cited

Pharmacology & ToxicologyNature CommunicationsPeer-reviewedAug 18, 2025

Molecular basis of ligand binding and receptor activation at the human A3 adenosine receptor

Liudi Zhang, Jesse I. Mobbs, Felix M. Bennetts…·David M. Thal

The paper presents cryo-EM structures of the human A3 adenosine receptor in three functional states, revealing a unique activation mechanism and a cryptic binding pocket.

9 citationstop 3%

humancryo-EM

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