Author

W. Tempel

University of TorontoORCID 0000-0003-3680-0678Unclaimed ORCID profile · follow to get notified of new preprints

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W. Tempel6 papers

Biology Disciplines

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Biophysics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:protein structure prediction· 2 Assay:cryo-EM· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:protein structure· 1

Frequent Co-Authors

Ali PunjaniiD· 1 shared Christina Wang· 1 shared CryoSPARC Team· 1 shared Dong ChengiD· 1 shared Fiona Hu· 1 shared Hannah R. BridgesiD· 1 shared Harris Snyder· 1 shared Jinrong MiniD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBiophysics

Ali PunjaniORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintOct 17, 2025

End-to-end automation of repeat-target cryo-EM structure determination in CryoSPARC

CryoSPARC Team, Kelly Barber, Hannah R. Bridges…·Nicholas Wong

This paper automates repeat-target cryo-EM structure determination in CryoSPARC, achieving high-resolution results for 21 GPCR datasets with minimal human intervention.

3 citations

cryo-EMdeep learning

𝕏 PostBluesky

Molecular BiologyCell chemical biologyPeer-reviewedMay 28, 2020

Structural basis for the binding selectivity of human CDY chromodomains

Dong Cheng, Yanli Liu, Tian‐Jie Lyu…·Jinrong Min

This study determines the structural basis for CDY chromodomain selectivity in binding lysine-methylated ARKS motifs, revealing distinct preferences for H3K9me3 and H3K27me3.

20 citations

humanprotein structure

𝕏 PostBluesky