Author
University of CambridgeORCID 0000-0001-6890-6050Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Jennifer Ross, Moescha Hoopman, Florian Küllmer…·Elisabeth C. Lowe
The paper identifies functional and structural differences among three GH172 arabinofuranosidases from Dysgonomonas gadei using synthetic substrates, covalent inhibitors, and structural analysis.
Hannah R. Bridges, Luka Bačić, Sebastian Deindl, Guillaume Gaullier
The paper identifies an intermediate conformation of ALC1 bound to a nucleosome's minor super-groove, revealing structural insights into its activation mechanism.
CryoSPARC Team, Kelly Barber, Hannah R. Bridges…·Nicholas Wong
This paper automates repeat-target cryo-EM structure determination in CryoSPARC, achieving high-resolution results for 21 GPCR datasets with minimal human intervention.
Miro A. Astore, Geoffrey Woollard, David Silva-Sánchez…·Sonya M. Hanson
The paper presents a cryo-EM conformational heterogeneity challenge to evaluate and improve methods for analyzing molecular motions in heterogeneous samples.
Bozhidar S. Ivanov, Hannah R. Bridges, Owen D. Jarman, Judy Hirst
The paper presents the structure of respiratory complex I from Paracoccus denitrificans in a turnover-ready state, revealing elements stabilizing the closed state and its relevance to mammalian complex I.