Yuyao Zhu

The paper determines cryo-EM structures of human ACC1 in inactive and activated states, revealing structural dynamics and regulatory mechanisms.

The paper reports high-resolution cryo-EM structures of human PCC and MCC, revealing substrate binding modes and biotin coordination mechanisms.

The paper develops BRET-based biosensors for evaluating SARS-CoV-2 3CLpro inhibitors in BSL-2 labs, showing they correlate with known inhibitor activities.