Molecular BiologybioRxivPreprint
High-coverage DNA sequence and modification profiling of targeted genomic elements using Nanopore-based Cas12a Targeted Ligation and Enrichment Sequencing (nCasTLES).
Samantha J. Vantine, Kensei Kishimoto, Brendan A Pacheco, William A. Flavahan
The paper introduces nCasTLES, a method for targeted sequencing using Cas12a to improve DNA sequence and modification profiling compared to nCATS.
DOI 10.64898/2026.08.25.747114