Ryan Zurakowski

This study shows that blocking lymphocyte entry into lymph nodes increases intracellular drug concentration for some antiretroviral drugs, but not others, due to changes in extracellular fluid volume.

This paper develops a high-fidelity 3D reconstruction pipeline for murine lymph nodes, enabling accurate modeling of drug transport and immune cell dynamics.

This paper develops a computational method to infer intercellular gene regulatory networks between different cell types using fluorescence reporter data and validates it through in silico case studies.

This study models HIV dynamics in lymph node sanctuary sites under antiretroviral therapy and finds that ongoing replication contributes very slowly to the total latent HIV pool.

The paper presents two models explaining the difference in HIV reservoir turnover rates with and without antiretroviral therapy and explores strategies for reservoir reduction.