Systems BiologyFrontiers in PhysiologyPeer-reviewed
Modeling the dynamics of Let-7-coupled gene regulatory networks linking cell proliferation to malignant transformation
Claude Gérard, Frédéric P. Lemaigre, Didier Gonze
The paper models how Let-7 couples cell cycle and transformation gene regulatory networks, showing their mutual control and role in cancer progression and tumor heterogeneity.
7 citations