RPE pseudopods maintain photoreceptor outer segment renewal despite subretinal space expansion in Adam9 knockout mice
Tylor R. Lewis, Carson M. Castillo, Sébastien Phan…·Vadim Y. Arshavsky
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University of California, DavisORCID 0000-0003-3766-2780Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
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Tylor R. Lewis, Carson M. Castillo, Sébastien Phan…·Vadim Y. Arshavsky
Gabriel Peinado, Prescott C. Alexander, Kaitryn E. Ronning…·Edward N. Pugh
The paper measures ERGs in mice to assess contributions of rod, RPE, and Müller glial cells to dark and light-driven changes in sub-retinal space ion concentrations.
Gabriel Peinado, Prescott C. Alexander, Kaitryn E. Ronning…·Edward N. Pugh
The paper develops a biophysical model of rod photoreceptors in mice to analyze the electroretinogram (ERG) a-wave, confirming that extracellular capacitive current and HCN1 channel activity shape the a-wave's relaxation and plateau.