Robel G. Alemu

This study evaluates the portability of polygenic indexes for behavioral traits across genetic ancestries, finding reduced accuracy in non-European populations and factors contributing to this loss.

This study identifies 10 novel genomic loci associated with intrinsic capacity using GWAS on UK Biobank and CLSA data, revealing genetic correlations with cellular processes and traits related to healthy aging.

The paper updates a polygenic index repository with more phenotypes, datasets, and improved causal inference methods, enhancing predictive performance and interpretability.