Xabier de Martin

The paper defines the DNA-binding syntax and chromatin remodeling capacities of bHLH transcription factors across cell differentiation, reprogramming, and cancer using integrated genomic and structural data.

The paper identifies mammalian-specific gene regulatory elements and their role in neocortical neuron subtype diversity and connectivity, linking them to neurodevelopmental disorders.

This study identifies SOX4, SOX11, and TFAP2D as critical regulators of ventropallial excitatory neuron development and PFC connectivity in mice, with conserved roles in humans.

The paper investigates the role of CAT-CAT E-boxes in neurogenesis, showing their association with chromatin accessibility, DNA demethylation, and evolutionary constraint through ChIP-seq, scRNA-seq, ATAC-seq, and DNA methylation data.