Author

Constantine George Lyketsos

Johns Hopkins UniversityORCID 0000-0003-3827-4720Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:imaging· 1 Assay:proteomics· 1

Frequent Co-Authors

Esther S. OhiD· 2 shared Paul B. RosenbergiD· 2 shared Ram SagariD· 2 shared Vasiliki MahairakiiD· 2 shared Abhay MoghekariD· 1 shared Anil MathuriD· 1 shared Anton B. IliukiD· 1 shared Ariadni XydiaiD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersGenetics

Esther S. OhORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintApr 29, 2026

Proteomic identification and validation of novel neuronal EV-based markers for Alzheimers disease biomarker discovery

Waqar Ahmed, Carlos J. Nogueras‐Ortiz, Ram Sagar…·Vasiliki Mahairaki

The paper identifies and validates novel neuronal EV surface markers, CNTNAP2 and STX1B, for Alzheimer's disease biomarker discovery through proteomic analysis of EVs from hiPSC-derived neurons and human brain.

DOI 10.64898/2026.04.26.720870

humanproteomics

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GeneticsCellsPeer-reviewedAug 2, 2023

Excitatory neurons derived from human induced Pluripotent Stem Cells show transcriptomic differences in Alzheimers patients from controls

Ram Sagar, Ioannis Azoidis, Cristina Zivko…·Dimitrios Avramopoulos

The paper compares transcriptomes of excitatory neurons from Alzheimer's patients and controls, identifying 621 differentially expressed genes and linking them to known Alzheimer's genes and functional networks.

9 citations

humanbulk RNA-seq

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NeuroscienceJournal of Nuclear MedicinePeer-reviewedMay 4, 2018

First in-human PET study of 3 novel tau radiopharmaceuticals: RO6958948

Dean Foster Wong, Robert A. Comley, Hiroto Kuwabara…·Edilio Borroni

This paper reports the first human PET study of three novel tau radiopharmaceuticals, finding that [18F]RO-948 shows superior characteristics for tau pathology characterization in Alzheimer's disease.

104 citationstop 1%

humanimaging

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