Alec L. Plotkin

This paper uses optimal transport to map CD8 T cell differentiation across time and tissues, revealing distinct migration waves and gene regulatory programs.

This paper benchmarks differential abundance methods to identify condition-specific cell subpopulations in multi-sample single-cell datasets, finding dataset-specific recommendations for method usage.

The paper investigates how sketching and graph generation methods affect the identification of biologically meaningful cell-populations in single-cell data, finding that sketching is more critical than graph construction.