William D. Green

This paper uses optimal transport to map CD8 T cell differentiation across time and tissues, revealing distinct migration waves and gene regulatory programs.

The paper uses in vivo single-cell gain-of-function screening to identify latent transcriptional programs that reprogram T cells into synthetic states with enhanced therapeutic potential.

This paper demonstrates that XCSgel, an injectable hydrogel, can localize and release immunotherapeutics to eliminate primary and abscopal murine triple-negative breast tumors with a single injection.