GeneticsbioRxivPreprint
Truncating ASXL1 mutations in Bohring-Opitz Syndrome dysregulate canonical and non-canonical Wnt Signaling
Isabella Lin, Angela Wei, Zain Awamleh…·Valerie A. Arboleda
The paper identifies how ASXL1 mutations disrupt the epigenome and activate Wnt signaling pathways in Bohring-Opitz syndrome and myeloid leukemias.