Eric Batchelor

SPIFEE is a pipeline that improves the analysis of live-cell fluorescence microscopy data by reducing noise and extracting features more accurately and objectively.

This study shows that p53 oscillations can be entrained by periodic DNA damage stimuli, leading to synchronized cell responses and altered cell-fate outcomes.

The paper investigates how cell state velocity influences quiescence-proliferation fate decisions in breast cancer under hypoxia, finding that inertia, not initial position, determines cell fate.