Vignesh Ram Somnath

Boltz-2 predicts protein–ligand affinity from its co-folded structures, nearing free-energy perturbation accuracy (average Pearson 0.66 on a 4-target FEP+ subset) at over 1000× lower compute.

ChromFormer predicts 3D chromatin structures from Hi-C data using a transformer-based model, outperforming existing methods on synthetic data and matching results on experimental data.