Author

Harald Steiner

German Center for Neurodegenerative DiseasesORCID 0000-0003-3935-0318Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:database / resource· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:protein sequence· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Christian HaassiD· 2 shared Frits KampiD· 2 shared Alessio Vittorio ColomboiD· 1 shared Andrea Steiner· 1 shared Andrew James MacphersoniD· 1 shared Arthur LiesziD· 1 shared Aswin VerhoeveniD· 1 shared Bettina Brunner· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersNeuroscience

Christian HaassORCID

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3 papers

Recent·Most cited

BioinformaticsJournal of Molecular BiologyPeer-reviewedJul 24, 2024

AAontology: An ontology of amino acid scales for interpretable machine learning

Stephan Breimann, Frits Kamp, Harald Steiner, Dmitrij Frishman

AAontology classifies 586 amino acid scales into 8 categories and 67 subcategories to improve interpretability in protein prediction tasks.

15 citations

protein sequencestatistical model

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NeuroscienceeLifePeer-reviewedApr 12, 2021

Microbiota-derived short chain fatty acids promote Aβ plaque deposition

Alessio Vittorio Colombo, Rebecca Sadler, Gemma Llovera…·Arthur Liesz

This study shows that microbiota-derived short chain fatty acids (SCFA) increase Aβ plaque deposition in Alzheimer's disease by promoting microglial activation and ApoE upregulation.

354 citationstop 1%

mouseexperimental assay

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NeuroscienceThe EMBO JournalPeer-reviewedAug 24, 2020

Intramembrane cleavage of TREM2 is determined by its intrinsic structural dynamics

Andrea Steiner, Kai Schlepckow, Bettina Brunner…·Franz Hagn

The paper investigates how structural dynamics of TREM2's transmembrane helix influence its intramembrane cleavage by gamma-secretase, linking flexibility to cleavage site specificity.

33 citations

humanprotein structure

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