Phyllis Thangaraj

This paper introduces TissueTox, an algorithm that predicts tissue toxicity of druggable proteins using multi-omic features and distinguishes between successful and failed drugs.

The paper compares machine learning algorithms for identifying acute ischemic stroke patients using EHR data, finding high accuracy with logistic regression and demonstrating generalizability.

The paper improves GWAS power for stroke by using machine learning to assign disease probabilities from electronic health records, discovering a novel variant associated with intracerebral hemorrhage.