Author

Rafael Machado Rezende

Brigham and Women's HospitalORCID 0000-0003-3998-8012Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Molecular Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Adriel Leal NóbileiD· 2 shared Anny Silva AdriiD· 2 shared Dennyson Leandro M. FonsecaiD· 2 shared Fernando Yuri Nery do ValeiD· 2 shared Gustavo Cabral‐MirandaiD· 2 shared Haroldo Dutra DiasiD· 2 shared Helder Imoto NakayaiD· 2 shared Ian Antunes Ferreira BahiaiD· 2 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersSystems Biology

Adriel Leal NóbileORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Systems BiologyTranslational PsychiatryPeer-reviewedNov 29, 2025

Integrative systems neuroimmunology reveals leukocyte-expressing PAX6 as a critical predictor of major depressive disorder

Haroldo Dutra Dias, Anny Silva Adri, Adriel Leal Nóbile…·Otávio Cabral-Marques

This study identifies PAX6 as a critical predictor of MDD using transcriptomic data from 3,114 individuals and validates its expression in PBMCs and the amygdala.

3 citations

humanbulk RNA-seq

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BioinformaticsbioRxivPreprintNov 13, 2024

Dysregulation of synaptic-related genes within neuroimmune networks of peripheral blood mononuclear cells in major depressive disorder

Anny Silva Adri, Adriel Leal Nóbile, Débora Gomes de Alburquerque…·Otávio Cabral-Marques

The paper identifies synaptic-related gene dysregulation in PBMCs of MDD patients, highlighting shared molecular signatures with brain regions and potential biomarkers for depression.

1 citation

humanbulk RNA-seq

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Molecular BiologyJournal of Hazardous MaterialsPeer-reviewedJun 25, 2021

An insight into neurotoxic and toxicity of spike fragments SARS-CoV-2 by exposure environment: A threat to aquatic health?

Ives Charlie‐Silva, Amanda P. C. Araújo, Abraão Tiago Batista Guimarães…·Guilherme Malafaia

This paper evaluates the aquatic toxicity of SARS-CoV-2 spike protein peptides on tadpoles, finding neurotoxic effects and oxidative stress.

37 citations

mouseexperimental assay

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