Cancer BiologybioRxivPreprint
Statins inhibit onco-dimerization of the 4Ig isoform of B7-H3
Margie Nicole Sutton, Sarah E. Glazer, Ajlan Al Zaki…·David R Piwnica-Worms
This study identifies statins as inhibitors of 4Ig-B7-H3 dimerization, linking their anti-cancer effects to immune checkpoint disruption in B7-H3-expressing tumors.
DOI 10.1101/2024.12.18.628944