Author
Commonwealth Scientific and Industrial Research OrganisationORCID 0000-0003-4018-2489Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
5 papers
Recent·Most cited
Priya Ramarao-Milne, Anubhav Kaphle, Roc Reguant…·Denis C. Bauer
The paper introduces synerOmics, a machine learning framework to identify synergistic protein interactions, finding ATL3 as a biomarker for lapatinib resistance in breast cancer.
Letitia M.F. Sng, Mitchell J. O’Brien, Brendan Hosking…·Natalie A. Twine
The paper identifies an epistatic interaction between RBMS3 and CDKN2B-AS1 in CAD risk using VariantSpark and BitEpi, with validation in UK Biobank and All of Us.
Letitia M.F. Sng, Anubhav Kaphle, Mitchell J. O’Brien…·Denis C. Bauer
The paper fine maps CAD loci in UK Biobank whole genome sequencing data using PolyFun and ML tools, showing improved sensitivity over traditional methods and demonstrating cost and speed benefits of cloud-based analysis.
Arash Bayat, Brendan Hosking, Yatish Jain…·Denis C. Bauer
BitEpi efficiently identifies higher-order epistatic interactions among SNVs in genetic data, outperforming existing methods in speed and accuracy.
Arash Bayat, Piotr Szul, Aidan R. O’Brien…·Denis C. Bauer
This paper introduces CursedForest, a Random Forest implementation that scales to millions of features and outperforms existing methods in speed.