Le Min Tan

The paper presents the first single-cell immune atlas of a Mainland Southeast Asian population, showing genetic ancestry shapes innate immune profiles and highlights sex-by-ancestry interactions in immune activation.

The paper presents AIDA, a diverse single-cell RNA-seq atlas of immune cells, revealing sub-continental diversity impacts on immune cell properties and identifying functional genetic variants.

The paper introduces scLinaX, a method to quantify X chromosome inactivation escape using scRNA-seq, revealing heterogeneity across cell types and tissues.

Monopogen calls single nucleotide variants from single-cell sequencing data, achieving high accuracy in germline variant detection and enabling ancestry inference and variant association analysis.