Verena Ruprecht

The paper shows that de novo E-cadherin/catenin complex formation at the phagocytic synapse regulates epithelial mechanics and force transmission for apoptotic cell clearance in zebrafish and mouse.

This paper develops a theoretical model to simulate phagocytosis of deformable targets and identifies three mechanical regimes based on target stiffness, validated experimentally with GUVs and lymphoma cells.

This study shows that reducing RhoA activity in aged HSCs lowers nuclear tension, restores chromatin structure, and improves regenerative capacity and lineage balance.

The paper identifies Srrm3-dependent microexons as critical for photoreceptor function and vision, showing their role in outer segment maintenance and their loss leading to blindness.