PathologybioRxivPreprint
Injury induced renal fibrosis promotes cystogenesis and cyst growth in adult mice with autosomal dominant polycystic kidney disease
Ming Wu, Dongping Chen, Yanzhe Wang…·Chaoyang Ye
This study shows that renal fibrosis induced by injury promotes cyst formation and growth in adult ADPKD mice, and targeting EZH2 can reduce fibrosis and cyst growth.
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