Hisao Tsukamoto

The paper characterizes and engineers a bistable cnidopsin from a coral that can switch between states using different light wavelengths, showing potential as an optogenetic tool for regulating Gs-signaling.

This study identifies five amino acid residues in mammalian melanopsins responsible for the specific interaction with the antagonist AA92593.

This paper characterizes a blue-sensitive, Gi/o-biased, and bistable ciliary opsin from a fan worm and explores its spectral and signaling properties through mutagenesis.