Author

Alexander F. Shida

University of WashingtonORCID 0000-0003-4140-6085Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:protein design· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Alex KangiD· 1 shared An‐Qi CheniD· 1 shared Asim K. BeraiD· 1 shared Bhanumathi Shankaran· 1 shared Brian CoventryiD· 1 shared David A. BakeriD· 1 shared Donald HilvertiD· 1 shared Donghyo KimiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Alex KangORCID

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1 paper

Recent·Most cited

BiochemistryNaturePeer-reviewedOct 14, 2026

De novo design of cysteine proteases

Hojae Choi, Magnus S. Bauer, Brian Coventry…·David A. Baker

This study designs de novo cysteine proteases with high activity and structural novelty, achieving 19% success rate and up to 3 x 10^7 rate enhancement over background reactions.

3 citationstop 5%

protein structuredeep learning

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