Author

Bhanumathi Shankaran

Lawrence Berkeley National Laboratory

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:protein design· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Alex KangiD· 1 shared Alexander F. ShidaiD· 1 shared An‐Qi CheniD· 1 shared Asim K. BeraiD· 1 shared Brian CoventryiD· 1 shared David A. BakeriD· 1 shared Donald HilvertiD· 1 shared Donghyo KimiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Alex KangORCID

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1 paper

Recent·Most cited

De novo design of cysteine proteases

Hojae Choi, Magnus S. Bauer, Brian Coventry, Preetham Venkatesh, An‐Qi Chen, Donghyo Kim, Asim K. Bera, Alex Kang, Hannah Nguyen, Shayan Sadre, Justin A. Decarreau, Emily Joyce, Bhanumathi Shankaran, Tuscan Rock Thompson, Gabriel Greenstein, , David A. Baker

This study designs de novo cysteine proteases with high activity and structural novelty, achieving 19% success rate and up to 3 x 10^7 rate enhancement over background reactions.

Nature · Oct 14, 2026Peer-reviewedBiochemistry