Author

James P. Nataro

University of VirginiaORCID 0000-0003-4159-0097Unclaimed ORCID profile · follow to get notified of new preprints

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James P. Nataro1 paper · University of Maryland, Baltimore

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Microbiology· 1

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Organism:mouse· 1

Frequent Co-Authors

Araceli E. SantiagoiD· 1 shared Fernando Ruı́z-PéreziD· 1 shared Guoqiang ZhuiD· 1 shared Jorge Luis Ayala-LujániD· 1 shared Lixia LiuiD· 1 shared Weijuan GongiD· 1 shared Yuexia LiaoiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

Araceli E. SantiagoORCID

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1 paper

Recent·Most cited

CD45-mediated apoptosis and IL2R downregulation by serine proteases from diarrheagenic bacteria

Yuexia Liao, Jorge Luis Ayala-Luján, Lixia Liu, Weijuan Gong, Guoqiang Zhu, James P. Nataro, Araceli E. Santiago, Fernando Ruı́z-Pérez

This paper shows that serine proteases from diarrheagenic bacteria cleave CD45 and induce T-cell apoptosis, mimicking IL-2 deprivation and contributing to bacterial virulence.

bioRxiv · Mar 20, 2025 · PreprintMicrobiology