BioinformaticsbioRxivPreprint
Activation of Disease-Associated Polycystin-1 Mutants by Binding of Stalk-derived Agonist Peptides
Keya Joshi, Brenda S. Magenheimer, Allan Haldane…·Yinglong Miao
The paper investigates how specific stalk-derived peptides can reactivate signaling in disease-associated PC1 mutants and uses computational simulations to support these findings.
DOI 10.64898/2026.10.10.758211