Author

Brenda S. Magenheimer

The University of Kansas Health System

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioinformatics· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Allan HaldaneiD· 2 shared Keya JoshiiD· 2 shared Robin L. MaseriD· 2 shared Yinglong MiaoiD· 2 shared Darren P. WallaceiD· 1 shared Dharmalingam SubramaniamiD· 1 shared Emily A. DanieliD· 1 shared Ericka Nevarez MunoziD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBioinformatics

Allan HaldaneORCID

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3 papers

Recent·Most cited

BioinformaticsbioRxivPreprintOct 12, 2026

Activation of Disease-Associated Polycystin-1 Mutants by Binding of Stalk-derived Agonist Peptides

Keya Joshi, Brenda S. Magenheimer, Allan Haldane…·Yinglong Miao

The paper investigates how specific stalk-derived peptides can reactivate signaling in disease-associated PC1 mutants and uses computational simulations to support these findings.

DOI 10.64898/2026.10.10.758211

protein structurestatistical model

𝕏 PostBluesky

BiochemistrybioRxivJan 6, 2024

Activation of Polycystin-1 Signaling by Binding of Stalk-derived Peptide Agonists

Shristi P. Pawnikar, Brenda S. Magenheimer, Keya Joshi…·Yinglong Miao

This study identifies stalk-derived peptides that activate PC1 signaling by binding to specific regions, revealing structural dynamics and potential therapeutic applications for ADPKD.

12 citations

humanproteomics

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GeneticsThe FASEB JournalPeer-reviewedApr 7, 2021

Quinomycin A reduces cyst progression in Polycystic Kidney Disease

Priyanka S. Radadiya, Mackenzie M. Thornton, Emily A. Daniel…·Madhulika Sharma

This study shows Quinomycin A reduces cyst progression in PKD by inhibiting Notch signaling and normalizing cilia lengths in a mouse model and human cells.

12 citations

mousehuman

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