GenomicsScientific ReportsPeer-reviewed
Discordant gene responses to radiation in humans and mice: hematopoietically humanized mice may save the day for radiation biomarker identification.
Shanaz A. Ghandhi, Lubomir B. Smilenov, Igor Shuryak…·Sally A. Amundson
The paper tests hematopoietically humanized mice as a model for radiation gene expression biomarkers, finding they better replicate human gene responses than standard mice.