GenomicsbioRxivPreprint
Genome-wide profiling of an enhancer-associated histone modification reveals the influence of asthma on the epigenome of the airway epithelium.
Peter K. McErlean, Audrey Kelly, Jaideep Dhariwal…·Paul Lavender
The paper identifies asthma-associated changes in H3K27ac enhancer marks in airway epithelial cells and validates their role in gene expression through CRISPR-based epigenome editing.