GeneticsThe Journal of DermatologyPeer-reviewed
A novel SERPINE1-FOSB fusion gene in a case of pseudomyogenic hemangioendothelioma results in activation of intact FOSB and the PI3K-AKT-mTOR signaling pathway and responsiveness to sirolimus
Jun Ren, Xiaohui Wang, Yulin Zhou…·Qiwei Guo
This study reports a novel SERPINE1-FOSB fusion gene in pseudomyogenic hemangioendothelioma that activates the PI3K-AKT-mTOR pathway and responds to sirolimus treatment.
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