Author

Isotta Landi

Icahn School of Medicine at Mount SinaiORCID 0000-0003-4212-4709Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Assay:electronic health records· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Assay:imaging· 1

Frequent Co-Authors

Alexander W. CharneyiD· 2 shared Andreas Meyer‐LindenbergiD· 1 shared Anthony J. BatzleriD· 1 shared Antonio Maria PersicoiD· 1 shared Ayman H. FanousiD· 1 shared Benjamin Scott GlicksbergiD· 1 shared Bonnie Auyeung BiD· 1 shared Brandon J. CoombesiD· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Alexander W. CharneyORCID

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3 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintApr 11, 2022

The contribution of genetic risk to the comorbidity of depression and anxiety: a multi-site electronic health records study

Brandon J. Coombes, Isotta Landi, Karmel W. Choi…·Joanna M. Biernacka

This study evaluates the association of genetic risk scores with depression and anxiety diagnoses, finding distinct genetic contributions to their comorbidity.

2 citations

humanelectronic health records

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Genetic & Genomic MedicineNature MedicinePeer-reviewedSep 1, 2021

Polygenic risk scores lack prognostic value for adults with severe mental illness

Isotta Landi, Deepak A. Kaji, Liam Cotter…·Alexander W. Charney

This study evaluates the prognostic value of polygenic risk scores for schizophrenia and finds they do not improve outcome prediction beyond clinical features.

59 citationstop 2%

humanGWAS summary statistics

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NeurosciencebioRxivPreprintMay 8, 2020

Differential neural circuitry behind autism subtypes with imbalanced social-communicative and restricted repetitive behavior symptoms

Natasha Bertelsen, Isotta Landi, Richard A. I. Bethlehem…·Michael Vincent Lombardo

The paper develops a phenotypic stratification model to predict autism subtypes based on SC-RRB balance and applies it to fMRI data, identifying subtype-specific neural circuitry and gene expression patterns.

DOI 10.1101/2020.05.08.083758

humanimaging

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