Michael Vincent Lombardo

The paper shows that excitation-inhibition balance is reflected in long-range cortical dynamics and is state-dependent, extending beyond fMRI to arousal-linked dynamics.

This study identifies a unique gaze fingerprint in humans that can be reliably detected across different stimuli and timeframes, with associations to autistic traits.

This study shows that a transient developmental excitation-inhibition imbalance causes lasting social brain circuit dysfunction in mice, with behavioral and transcriptional consequences.

This study investigates developmental dysconnectivity in 22q11.2 deletion syndrome using a cross-species approach, finding age-specific fMRI connectivity changes with synaptic origins.

The paper identifies hypo- and hyperconnectivity subtypes in autism using cross-species fMRI, linking them to distinct biological mechanisms in mice and humans.

The paper examines sex differences in brain structure at birth in newborns, finding larger brain volumes in males and specific regional differences in gray and white matter volumes between sexes.

This study shows that Ube3a gene overdosage causes sex-biased effects on brain connectivity, behavior, and gene expression in mice, linking it to autism-related phenotypes.

This study identifies 928 genes associated with brain weight variation across three datasets and links them to neurodevelopmental processes and brain function.

The paper identifies patterns of neural variability in autism using fMRI across tasks, finding greater global connectivity deviations and similar spatial patterns in autistic individuals compared to controls.

The paper identifies a multimodal brain pattern associated with autism by integrating gray and white matter morphology data and linking it to clinical symptoms.

The paper links mTOR-related synaptic pathology to functional hyperconnectivity in autism using mouse models and human fMRI data.

The paper examines functional connectivity in toddlers with autism, finding disrupted links between temporal-visual cortex and communication/social abilities, particularly in those with poor social engagement.

The paper identifies atypical genomic cortical patterning in autistic toddlers with poor early language outcome, linking it to prenatal developmental processes and later functional specialization.

The paper identifies atypical brain asymmetry in autism as a potential neurophenotype for stratification, showing individualized patterns linked to symptom severity and language delay.

The paper shows that the Hurst exponent from fMRI BOLD signals indexes synaptic excitation-inhibition ratio, revealing sex-specific E:I imbalance in autistic mice medial prefrontal cortex.

This study examines the boundary sharpness coefficient (BSC) as a measure of cortical microstructure in ASD, finding age, sex, and regional differences in BSC that correlate with clinical measures.

This study investigates reward processing in autism spectrum disorder (ASD) and finds generalized hypoactivity in the ventral striatum during anticipation of both social and monetary rewards.

The paper develops a phenotypic stratification model to predict autism subtypes based on SC-RRB balance and applies it to fMRI data, identifying subtype-specific neural circuitry and gene expression patterns.

This study examines how oxytocin affects salivary testosterone and oestradiol levels in autistic and typical women, finding distinct hormonal responses between groups.

The paper models cortical thickness in autistic males relative to typically-developing age norms, identifying a subgroup with significant age-deviant cortical thickness.

This paper discusses the importance of big data approaches for understanding heterogeneity in autism and highlights the need for both supervised and unsupervised methods to model variability across multiple levels of analysis.

The paper investigates how prenatal androgens affect functional connectivity in social brain networks, finding sex-specific impacts on adolescent males.

Across 5,216 UK Biobank adults, males had larger brain volumes and surface areas, females thicker cortices and stronger default-mode connectivity; male variance was generally greater.

The paper identifies 10 differentially expressed co-expression modules in ASD cortex, showing coordinated dysregulation of transcriptional programs rather than independent pathways.

This study shows oxytocin increases corticostriatal connectivity in women, with effects linked to autistic traits and potential implications for neuropsychiatric conditions.

This study examines how mindfulness relates to dynamic functional neural connectivity in children, finding that higher mindfulness is associated with greater neural state transitions and reduced anxiety.