Author

Claudia Jessen‐Trefzer

University of FreiburgORCID 0000-0003-4216-8189Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Mariia Zmyslia· 1 shared Martin HolzeriD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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2 top collaborators · 1 mutual co-author link

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1 shared paperCancer Biology

Mariia Zmyslia

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintSep 11, 2025

Customized Protein Nanoreactors for Affibody-Directed Activation of 5-Fluorcytosin in HER2-Positive Cells

Mariia Zmyslia, Martin Holzer, Claudia Jessen‐Trefzer

This paper develops encapsulin nanoreactors that target HER2-positive cells and convert 5-fluorocytosine into 5-fluorouracil, reducing cell viability by 83%.

DOI 10.1101/2025.09.11.675605

humanproteomics

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