BiochemistryNature Chemical BiologyPeer-reviewed
p53 protein abundance is a therapeutic window across TP53 mutant cancers and is targetable with proximity inducing small molecules
Ananthan Sadagopan, Maximilian Carson, Eriks J. Zamurs…·William J. Gibson
The paper shows that p53 protein abundance in TP53 mutant cancers can be exploited to selectively kill these cells using proximity-inducing small molecules.
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