Author

Diego A. Leonardo

Universidade de São PauloORCID 0000-0003-4264-3074Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:protein structure· 2 Approach:biophysical modeling· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1 Organism:rat· 1

Frequent Co-Authors

Adam J. SimpkiniD· 1 shared Adolfo B. PomaiD· 1 shared Ana Paula Ulian de AraújoiD· 1 shared Clarice IzumiiD· 1 shared Cleidy Osorio-MogollóniD· 1 shared Dan Erick Vivas-RuiziD· 1 shared Daniel John RigdeniD· 1 shared Giovanna Christe dos Reis SaladinoiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperMolecular Biology

Adam J. SimpkinORCID

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3 papers

Recent·Most cited

BiophysicsbioRxivPreprintMay 7, 2026

Structural modelling and biophysical analyses reveal a dimeric coiled-coil architecture in the FAZ10 central region of Trypanosoma brucei

Cleidy Osorio-Mogollón, Diego A. Leonardo, Clarice Izumi…·Munira Muhammad Abdel Baqui

This study determines the dimeric coiled-coil structure of the FAZ10 central region in Trypanosoma brucei using structural modeling and biophysical analysis.

DOI 10.64898/2026.05.05.722045

humanmouse

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Molecular BiologybioRxivPreprintApr 22, 2023

A Key Piece of the Puzzle: The central tetramer of the Saccharomyces cerevisiae septin protofilament and Its Implications for Self-Assembly

Rafael Marques da Silva, Giovanna Christe dos Reis Saladino, Diego A. Leonardo…·Richard Charles Garratt

The paper presents the first crystal structure of a yeast septin heterodimer, providing insights into the structural biology of yeast septins and their interfaces.

2 citations

yeastexperimental assay

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Molecular BiologyIUCrJPeer-reviewedDec 1, 2021

Identification of unknown proteins in X-ray crystallography and cryo-EM

Grzegorz Chojnowski, Adam J. Simpkin, Diego A. Leonardo…·Daniel John Rigden

The paper presents an automated pipeline to identify protein sequences from cryo-EM and crystallographic data, demonstrating its application on an unknown snake venom protein.

62 citations

protein structureexperimental assay

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