Cell BiologyEMBO ReportsPeer-reviewed
Sequestration of the polyunsaturated fatty acids protects the cells with oxidative phosphorylation deficiency from ferroptosis
Guillermo Puertas-Frias, María José Saucedo-Rodríguez, Kristýna Čunátová…·Alena Pecinová
The paper identifies that OXPHOS-deficient cells sequester polyunsaturated fatty acids into triacylglycerols to protect against ferroptosis, observed in patient fibroblasts and hypoxia conditions.
DOI 10.1038/s44319-026-00898-y