Author

Christopher J. Kim

University of MinnesotaORCID 0000-0003-4305-0473Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Approach:diffusion model· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein design· 1 Assay:protein structure· 1 Assay:structural biology· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Andrew P. HinckiD· 1 shared Brian CoventryiD· 1 shared Buwei HuangiD· 1 shared Clara McCurdyiD· 1 shared Cynthia S. HinckiD· 1 shared David A. BakeriD· 1 shared David S. LeeiD· 1 shared Dionne K. VafeadosiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Andrew P. HinckORCID

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1 paper

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedJan 10, 2026

✦ In-depth digest

Improved protein binder design using -pairing targeted RFdiffusion

Isaac Sappington, Martin Toul, David S. Lee…·David A. Baker

Conditioning RFdiffusion on edge beta-strand pairing yields specific binders to polar targets, with in silico success above 9.2% versus 0.98% for hotspot-only conditioning.

33 citationstop 1%

protein structurestructural biology

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