John Li Chen

This study shows that LRRK2 kinase activity affects BMP and GSL levels in lysosomes, linking lysosomal dysfunction to Parkinson's disease through changes in GCase activity and BMP accumulation.

The paper describes a novel repression-derepression mechanism for Staphylococcus aureus pathogenicity islands (SaPIs) involving tetrameric repressors and an inducing protein.

This study shows that the gustatory insular cortex in mice is crucial for decision-making during a taste-based reward task, with cognitive signals during a delay period driving behavior.