Author

Saffron R. Little

University of MichiganORCID 0000-0003-4314-3979Unclaimed ORCID profile · follow to get notified of new preprints

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Approach:experimental assay· 1

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Aravintha SivaiD· 1 shared John P. GilliesiD· 1 shared Morgan E. DeSantisiD· 1 shared William Olaf HancockiD· 1 shared

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2025-2025 · peak 1/yr

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Aravintha SivaORCID

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1 paper

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BiophysicsJournal of Biological ChemistryPeer-reviewedFeb 26, 2025

Cargo adaptor identity controls the mechanism and kinetics of dynein activation

John P. Gillies, Saffron R. Little, Aravintha Siva…·Morgan E. DeSantis

The paper investigates how different cargo adaptors influence the kinetics and mechanism of dynein-dynactin complex formation, revealing distinct assembly pathways and stable tripartite complexes.

9 citationstop 5%

experimental assay

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