NeuroscienceMolecular NeurobiologyPeer-reviewed
Absence of receptor for advanced glycation end product (RAGE) reduces inflammation and extends survival in the hSOD1G93A mouse model of amyotrophic lateral sclerosis
John D. Lee, Tanya S. McDonald, Jenny N. Fung, Trent M. Woodruff
This study shows that removing RAGE signaling in SOD1G93A mice slows ALS progression, extends survival, and reduces neuroinflammation and oxidative stress.
35 citations