Author

Steven John Kiddle

King's College LondonORCID 0000-0003-4350-7437Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:differential expression· 2 Approach:statistical model· 2 Approach:Bayesian inference· 1 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Richard DobsoniD· 3 shared Alzheimer’s Disease Neuroimaging Initiative· 2 shared Caroline JohnstoniD· 2 shared Nicola Voyle· 2 shared Alice Carla Luisa ParodiiD· 1 shared Amos FolariniD· 1 shared and for the Coalition Against Major Diseases (CAMD)· 1 shared Angela HodgesiD· 1 shared

Activity by Year

2017-2018 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersGenetics

Richard DobsonORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

GeneticsbioRxivPreprintFeb 22, 2018

Genetic meta-analysis identifies 9 novel loci and functional pathways for Alzheimers disease risk

Iris E. Jansen, Jeanne E. Savage, Kyoko Watanabe…·Daniëlle Posthuma

This study identifies 9 novel genetic loci and 215 potential causative genes associated with Alzheimer's disease risk through a large genome-wide association analysis.

30 citations

humanGWAS summary statistics

𝕏 PostBluesky

BioinformaticsbioRxivPreprintAug 10, 2017

Does genetic risk help to predict amyloid burden in a non-demented population? A Bayesian approach.

Nicola Voyle, Willemijn J. Jansen, Aoife Keohane…·EDAR and DESCRIPA study groups

This study uses Bayesian logistic regression to assess if genetic risk factors predict amyloid burden in non-demented individuals, finding that known factors like age and APOE are more predictive than polygenic risk scores.

1 citation

humanproteomics

𝕏 PostBluesky

NeurosciencebioRxivPreprintJul 11, 2017

Heterogeneity of cognitive decline in dementia: a failed attempt to take into account variable time-zero severity

Steven John Kiddle, Alice Carla Luisa Parodi, Caroline Johnston…·and for the Coalition Against Major Diseases (CAMD)

The paper explores Temporal Clustering to address time-zero selection in longitudinal cognitive decline studies but concludes the method has biases and is discontinued.

2 citations

humanbulk RNA-seq

𝕏 PostBluesky