Bladder mucosal afferents detect UTI and aid pathogen clearance
Cindy Tay, Harman Sharma, Stewart Ramsay, Georgia Bourlotos, Sarah K Manning, Natalie E. Stevens, Sophie J. Miller, Geraint B. Rogers, David John Lynn, Feargal J. Ryan, Andrea M. Harrington, Vladimir P. Zagorodnyuk, Steven Taylor, Luke Grundy
This study identifies bladder mucosal afferents as key sensors of UTI, showing they drive pain and urinary frequency during infection, aiding bacterial clearance.
Proceedings of the National Academy of Sciences · Aug 3, 2026Peer-reviewedNeuroscience