Author

Luke Grundy

Flinders UniversityORCID 0000-0002-3900-7141Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:database / resource· 1 Assay:metagenomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrea M. HarringtoniD· 2 shared Feargal J. RyaniD· 2 shared Ashlee Caldwell· 1 shared Cindy TayiD· 1 shared Clarice M. HarkeriD· 1 shared Cong M. PhamiD· 1 shared David GrundyiD· 1 shared David John LynniD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersNeuroscience

Andrea M. HarringtonORCID

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3 papers

Recent·Most cited

NeuroscienceProceedings of the National Academy of SciencesPeer-reviewedAug 3, 2026

Bladder mucosal afferents detect UTI and aid pathogen clearance

Cindy Tay, Harman Sharma, Stewart Ramsay…·Luke Grundy

This study identifies bladder mucosal afferents as key sensors of UTI, showing they drive pain and urinary frequency during infection, aiding bacterial clearance.

DOI 10.1073/pnas.2604124123

mouseexperimental assay

𝕏 PostBluesky

BioinformaticsbioRxivPreprintApr 19, 2026

OpusTaxa: A Unified Workflow for Taxonomic Profiling, Assembly, and Functional Analysis of Shotgun Metagenomes

Yen-Kai Chen, Clarice M. Harker, Cong M. Pham…·Feargal J. Ryan

OpusTaxa provides an open-source workflow for streamlined shotgun metagenomic analysis, enabling taxonomic profiling, assembly, and functional analysis with minimal user configuration.

DOI 10.64898/2026.04.15.718825

metagenomicsstatistical model

𝕏 PostBluesky

NeuroscienceJournal of NeurosciencePeer-reviewedMar 16, 2021

Activation of MrgprA3 and MrgprC11 on bladder-innervating afferents induces peripheral and central hypersensitivity to bladder distension

Luke Grundy, Ashlee Caldwell, Sonia Garcia‐Caraballo…·Stuart M. Brierley

This study identifies MrgprA3 and MrgprC11 as functional receptors on bladder afferents that induce hypersensitivity to distension when activated, offering a potential therapeutic target for bladder disorders.

18 citations

mouseexperimental assay

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