Author

Leslie Recio

Integrated Laboratory Systems, Inc.ORCID 0000-0003-4392-6412Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:benchmarking· 2 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Andrew WilliamsiD· 2 shared Charles C. ValentineiD· 2 shared Elizabeth K. SchmidtiD· 2 shared Fang Yin LoiD· 2 shared Jesse J. SalkiD· 2 shared Kristine L. WittiD· 2 shared Miriam V. RivasiD· 2 shared Stephanie L. Smith‐RoeiD· 2 shared

Activity by Year

2015-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersGenomics

Andrew WilliamsORCID

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3 papers

Recent·Most cited

GenomicsMutation Research/Genetic Toxicology and Environmental MutagenesisPeer-reviewedAug 2, 2023

Adopting Duplex Sequencing Technology for Genetic Toxicity Testing: A Proof-of-Concept Mutagenesis Experiment with N-Ethyl-N-Nitrosourea (ENU)-Exposed Rats

Stephanie L. Smith‐Roe, Cheryl A. Hobbs, Victoria Hull…·Kristine L. Witt

This paper evaluates a DuplexSeq-based mutagenesis assay in ENU-exposed rats, showing early detection of mutations and reproducible results across tissues and labs.

23 citations

ratwhole-genome sequencing

𝕏 PostBluesky

GenomicsbioRxivPreprintFeb 22, 2023

Error-corrected Duplex Sequencing enables direct detection and quantification of mutations in human TK6 cells with remarkable inter-laboratory consistency

Eunnara Cho, Carol D. Swartz, Andrew Williams…·Carole Lyn Yauk

This study demonstrates that error-corrected Duplex Sequencing reliably detects and quantifies mutations in human TK6 cells across different laboratories and time points.

2 citations

humanwhole-genome sequencing

𝕏 PostBluesky

GeneticsToxicological SciencesPeer-reviewedSep 10, 2015

Mining the archives: a cross-platform analysis of gene expression profiles in archival formalin-fixed paraffin-embedded (FFPE) tissue

Anna Francina Webster, Paul Zumbo, Jennifer Fostel…·Christopher E Mason

This study evaluates gene expression profiles from FFPE and fresh-frozen mouse liver tissues using various methods, finding ribo-depletion RNA-seq provides the best results for FFPE samples.

DOI 10.1093/toxsci/kfv195

mousebulk RNA-seq

𝕏 PostBluesky