Author

Christine Crute

Health and Environmental Sciences InstituteORCID 0000-0003-4400-505XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:imaging· 1 Approach:machine learning (classical)· 1 Research Focus:perturbation response prediction· 1 Assay:perturbation screen· 1

Frequent Co-Authors

Alex BäuerleiD· 1 shared Alex Beatson· 1 shared Ángel Alexander CabreraiD· 1 shared Anne Elizabeth CarpenteriD· 1 shared Beth A. CiminiiD· 1 shared Bram L. GorisseniD· 1 shared Brandon WhiteiD· 1 shared Daniil A. BoikoiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPharmacology & Toxicology

Alex BäuerleORCID

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1 paper

Recent·Most cited

Pharmacology & ToxicologyCell SystemsPeer-reviewedMar 27, 2026

✦ In-depth digest

Cell Painting for cytotoxicity and mode-of-action analysis in primary human hepatocytes

Jessica Ewald, Katherine Titterton, Alex Bäuerle…·Shantanu Singh

Cell Painting in primary human hepatocytes exposed to 1,085 compounds detects bioactivity at lower concentrations than cytotoxicity assays and predicts cell-based, but not cell-free, ToxCast endpoints across feature extractors.

16 citationstop 1%

humanimaging

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