Author

Christopher Herodotou

Indiana University School of MedicineORCID 0000-0003-4452-4597Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Aditi Sanjay KhatpeiD· 1 shared Anna Maria StornioloiD· 1 shared Cihat ErdoğaniD· 1 shared Duojiao CheniD· 1 shared George Earl SanduskyiD· 1 shared Harikrishna NakshatriiD· 1 shared Henry Elmer MangiD· 1 shared Hongyu GaoiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Aditi Sanjay KhatpeORCID

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1 paper

Recent·Most cited

Cancer BiologyCancer Research CommunicationsPeer-reviewedDec 7, 2023

BRCA1 and BRCA2 germline mutations driven signaling pathway alterations are sufficient to initiate breast tumorigenesis by the PIK3CAH1047R oncogene.

Poornima Bhat‐Nakshatri, Aditi Sanjay Khatpe, Duojiao Chen…·Harikrishna Nakshatri

This paper compares single-cell transcriptomes of BRCA1/2 mutation carriers and non-carriers to show how these mutations alter signaling pathways and drive breast cancer development through PIK3CA mutations.

14 citations

humanscRNA-seq

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