Maciej Parys

SpeciefAI generates species-specific mRNA and protein sequences for antibodies and nanobodies using a transformer model trained on six species.

DoggifAI translates non-canine antibody sequences into canine ones using a transformer model, generating species-appropriate framework regions and preserving binding specificity.

The paper compares immune checkpoint expression in canine and human cancers, identifying similarities and differences that suggest potential for immunotherapy models.

The paper develops COD-dipp to map MHC Class I antigens from cancer studies and identifies immune-relevant genomic regions for vaccine design.